Concepedia

Paraoxonase-2 Reduces Oxidative Stress in Vascular Cells and Decreases Endoplasmic Reticulum Stress–Induced Caspase Activation

Sven Horke, Ines Witte, Petra Wilgenbus, Maximilian Krüger, Dennis Strand, Ulrich Förstermann

Circulation · 2007 · 244 citations · 23 references

DOIFull text

Open access

Abstract

We suggest that PON2 represents an endogenous defense mechanism against vascular oxidative stress and unfolded protein response-induced cell death, thereby contributing to the prevention of atherosclerosis.

References

23

THE MAMMALIAN UNFOLDED PROTEIN RESPONSE

Martin Schröder, Randal J. Kaufman · Annual Review of Biochemistry · 2005 · 3K citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

Jan Kyhse‐Andersen · Journal of Biochemical and Biophysical Methods · 1984 · 2.5K citations

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Identification of the cis-Acting Endoplasmic Reticulum Stress Response Element Responsible for Transcriptional Induction of Mammalian Glucose-regulated Proteins

Hiderou Yoshida, Kyosuke Haze, Hideki Yanagi et al. · Journal of Biological Chemistry · 1998 · 1.2K citations · Full text

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

Michael Aviram, Mira Rosenblat, C L Bisgaier et al. · Journal of Clinical Investigation · 1998 · 1.1K citations · Full text

, , +15

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

Bo Feng, Pin Mei Yao, Yankun Li et al. · Nature Cell Biology · 2003 · 865 citations

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