Roger S. Newton

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

Michael Aviram, Mira Rosenblat, C L Bisgaier et al. · Journal of Clinical Investigation · 1998 · 1.1K citations · Full text

Possible Peroxidative Role, Redox Signaling, Hdl Levels +15

Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants

Michael Aviram, Mira Rosenblat, Scott S. Billecke et al. · Free Radical Biology and Medicine · 1999 · 600 citations

Biochemistry, Lipid Peroxidation, Bioanalysis +8

Paraoxonase Active Site Required for Protection Against LDL Oxidation Involves Its Free Sulfhydryl Group and Is Different From That Required for Its Arylesterase/Paraoxonase Activities

Michael Aviram, Scott S. Billecke, Robert C. Sorenson et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 451 citations · Full text

Aldo-keto Reductase, Lipid Peroxidation, Free Sulfhydryl Group +16

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Stephen L. Pinkosky, Roger S. Newton, Emily A. Day et al. · Nature Communications · 2016 · 447 citations · Full text

Atorvastatin and gemfibrozil metabolites, but not the parent drugs, are potent antioxidants against lipoprotein oxidation

Michael Aviram, Mira Rosenblat, Charles L. Bisgaier et al. · Atherosclerosis · 1998 · 300 citations

Gemfibrozil Metabolites, Oxysterol, Biochemistry +11