Roger S. Newton

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

Mira Rosenblat, C L Bisgaier, Roger S. Newton et al. · Journal of Clinical Investigation · 1998 · 1.2K citations · Full text

Life Sciences, Biochemistry, Lipid Biochemistry +16

Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants

Michael Aviram, Mira Rosenblat, Scott S. Billecke et al. · Free Radical Biology and Medicine · 1999 · 600 citations

Life Sciences, Biochemistry, Redox Biochemistry +7

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Stephen L. Pinkosky, Roger S. Newton, Emily A. Day et al. · Nature Communications · 2016 · 481 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Paraoxonase Active Site Required for Protection Against LDL Oxidation Involves Its Free Sulfhydryl Group and Is Different From That Required for Its Arylesterase/Paraoxonase Activities

Michael Aviram, Scott S. Billecke, Robert C. Sorenson et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 454 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Atorvastatin and gemfibrozil metabolites, but not the parent drugs, are potent antioxidants against lipoprotein oxidation

Michael Aviram, Mira Rosenblat, Charles L. Bisgaier et al. · Atherosclerosis · 1998 · 300 citations

Life Sciences, Biochemistry, Pharmacology +16