Stephen L. Pinkosky

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Stephen L. Pinkosky, Roger S. Newton, Emily A. Day et al. · Nature Communications · 2016 · 481 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism

Stephen L. Pinkosky, Jeffrey C. Hanselman, Cheryl D. Bradshaw et al. · Journal of Lipid Research · 2012 · 236 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

Marisa R. Morrow, Battsetseg Batchuluun, Jianhan Wu et al. · Cell Metabolism · 2022 · 180 citations

Life Sciences, Biochemistry, Pharmacology +12

Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity

Rebecca J. Ford, Morgan D. Fullerton, Stephen L. Pinkosky et al. · Biochemical Journal · 2015 · 154 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms

Stephen L. Pinkosky, John W. Scott, Eric M. Desjardins et al. · Nature Metabolism · 2020 · 135 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14