Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)

The role of autophagy during the early neonatal starvation period

Akiko Kuma, Masahiko Hatano, Makoto Matsui et al. · Nature · 2004 · 2.8K citations

Life Sciences, Cell Biology, Physiology +11

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.

Luke Whitesell, Edward G. Mimnaugh, B. de Costa et al. · Proceedings of the National Academy of Sciences · 1994 · 1.4K citations

Life Sciences, Molecular Biology, Pharmacology +14

NF-κB-Inducing Kinase Regulates the Processing of NF-κB2 p100

Gutian Xiao, Edward W. Harhaj, Shao‐Cong Sun · Molecular Cell · 2001 · 825 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8

Autophagic programmed cell death by selective catalase degradation

Li Yu, Fengyi Wan, Sudeshna Dutta et al. · Proceedings of the National Academy of Sciences · 2006 · 661 citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Akt Forms an Intracellular Complex with Heat Shock Protein 90 (Hsp90) and Cdc37 and Is Destabilized by Inhibitors of Hsp90 Function

Andrea Basso, David B. Solit, Gabriela Chiosis et al. · Journal of Biological Chemistry · 2002 · 626 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15