The role of autophagy during the early neonatal starvation period

Akiko Kuma, Masahiko Hatano, Makoto Matsui, +6

Nature

NutritionMitophagyEnergy HomeostasisDevelopmental BiologyCell Autophagy +6

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

Noboru Mizushima, Akiko Kuma, Yoshinori Kobayashi, +6

Journal of Cell Science

Autophagy Is Essential for Preimplantation Development of Mouse Embryos

Satoshi Tsukamoto, Akiko Kuma, Mirei Murakami, +3

Science

OocyteFertilityGeneticsReproductive BiologyEarly Embryos +17

LC3, an Autophagosome Marker, Can be Incorporated into Protein Aggregates Independent of Autophagy: Caution in the Interpretation of LC3 Localization

Akiko Kuma, Makoto Matsui, Noboru Mizushima

Autophagy

MitophagyYeast Atg8Molecular BiologyCytoskeletonProtein Aggregates Independent +17

Formation of the ∼350-kDa Apg12-Apg5·Apg16 Multimeric Complex, Mediated by Apg16 Oligomerization, Is Essential for Autophagy in Yeast

Akiko Kuma, Noboru Mizushima, Naotada Ishihara, +1

Journal of Biological Chemistry

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

Anne Simonsen, Hanne C. G. Birkeland, David J. Gillooly, +6

Journal of Cell Science

Protein SecretionMolecular BiologyAutophagic Membrane TrafficCell AutophagyAutophagy +15

LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury

Shuhei Nakamura, Saki Shigeyama, Satoshi Minami, +26

Nature Cell Biology

InflammationLysosomal Damage ResponseRenal FunctionLc3 LipidationBiochemistry +12

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Tetsuya Saito, Akiko Kuma, Yuki Sugiura, +16

Nature Communications

Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons

Saori R. Yoshii, Akiko Kuma, Takumi Akashi, +8

Developmental Cell

Knockout MouseNeuroregenerationDevelopmental BiologyCell DeathStem Cell Research +8

Proteasome-dependent Activation of Mammalian Target of Rapamycin Complex 1 (mTORC1) Is Essential for Autophagy Suppression and Muscle Remodeling Following Denervation

Pham Nguyen Quy, Akiko Kuma, Philippe Pierre, +1

Journal of Biological Chemistry