Gabriela Chiosis

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

Haley Hieronymus, Justin Lamb, Kenneth N. Ross et al. · Cancer Cell · 2006 · 621 citations · Full text

Bioinformatics, Systems Biology, Natural Sciences +14

Akt Forms an Intracellular Complex with Heat Shock Protein 90 (Hsp90) and Cdc37 and Is Destabilized by Inhibitors of Hsp90 Function

Andrea Basso, David B. Solit, Gabriela Chiosis et al. · Journal of Biological Chemistry · 2002 · 620 citations · Full text

Heterodimeric JAK–STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

Priya Koppikar, Neha Bhagwat, Outi Kilpivaara et al. · Nature · 2012 · 359 citations · Full text

New Arylthioindoles:  Potent Inhibitors of Tubulin Polymerization. 2. Structure−Activity Relationships and Molecular Modeling Studies

Gabriella Martino, Michael Edler, Giuseppe La Regina et al. · Journal of Medicinal Chemistry · 2006 · 356 citations

Pharmaceutical Science, Chemical Biology, Pharmaceutical Chemistry +16

Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

Eloisi Caldas-Lopes, Leandro Cerchietti, James H. Ahn et al. · Proceedings of the National Academy of Sciences · 2009 · 309 citations · Full text

Hsp90 Inhibitor Pu-h71, Breast Oncology, Complete Responses +15