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Toxicity and effectivity of high-dose Idarubicin during AML induction therapy: Results of a pilot study in children

DOI

14

Citations

0

References

2000

Year

Ursula Creutzig, Dieter Körholz, C. Niemeyer, H. Kabisch, Norbert Graf, Alfred Reiter, H. Scheel-Walter, C Bender-Götze, Wolfgang Behnisch, J Hermann,
Klinische Pädiatrie

Abstract

Results of this pilot study show that the IDR 14 mg/m2 regimen was effective but also toxic. According to our results which, however, are based on small patient numbers, an improved outcome compared to the IDR 12 mg/m2 regimen seems to be unlikely, therefore the possibly increased toxicity might not be acceptable.