Concepedia

Dose Escalation

Dose Escalation is a clinical trial methodology involving the systematic increase of therapeutic agent dosage across successive patient cohorts to determine the optimal balance between efficacy and safety in the context of cell or gene therapy translation.

2.5K

Publications

177.3K

Citations

19.5K

Authors

4K

Institutions

Publications per year

2017–2026

835

Parents

Children

Publications

2.5K

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN

Hartmut Döhner, Andrew H. Wei, Frederick R. Appelbaum et al. · Blood · 2022 · 3K citations · Full text

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Management of toxicities from immunotherapy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

John B.A.G. Haanen, Franck Carbonnel, Caroline Robert et al. · Annals of Oncology · 2017 · 2.4K citations · Full text

, , +12

Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia

Francesco Lo‐Coco, Giuseppe Avvisati, Marco Vignetti et al. · New England Journal of Medicine · 2013 · 1.6K citations · Full text

, , +17

Decitabine improves patient outcomes in myelodysplastic syndromes

Hagop M. Kantarjian, Jean‐Pierre J. Issa, C Rosenfeld et al. · Cancer · 2006 · 1.5K citations

, , +14

Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients

Zhixiang Shen, Guoqiang Chen, Jian-Hua Ni et al. · Blood · 1997 · 1.4K citations

, , +17

1–5 of 2.5K

Authors

19.5K

  1. HM
    Hagop M. Kantarjian

    The University of Texas MD Anderson Cancer Center, United States

    85 publications · 12.9K citations

    43

    h-index

  2. JE
    Jörge E. Cortes

    The University of Texas MD Anderson Cancer Center, United States

    63 publications · 7K citations

    36

    h-index

  3. MJ
    Mark J. Levis

    Johns Hopkins University, United States

    31 publications · 3.7K citations

    25

    h-index

  4. GG
    Guillermo Garcia‐Manero

    The University of Texas MD Anderson Cancer Center, United States

    39 publications · 3.8K citations

    25

    h-index

  5. FR
    Farhad Ravandi

    The University of Texas MD Anderson Cancer Center, United States

    44 publications · 6.1K citations

    25

    h-index

1–5 of 19.5K

Institutions

4K

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    86 h-index

    1.4K publications

    135.9K citations

  2. Memorial Sloan Kettering Cancer Center

    New York, United States

    60 h-index

    537 publications

    122.7K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    48 h-index

    343 publications

    40K citations

  4. Massachusetts General Hospital

    Boston, United States

    43 h-index

    179 publications

    18.9K citations

  5. Cornell University

    Ithaca, United States

    41 h-index

    288 publications

    88.3K citations

  6. Northwestern University

    Evanston, United States

    40 h-index

    136 publications

    9.3K citations

  7. University of Pennsylvania

    Philadelphia, United States

    39 h-index

    167 publications

    24.6K citations

  8. Johns Hopkins University

    Baltimore, United States

    38 h-index

    175 publications

    19.8K citations

1–8 of 4K

Venues

  1. Journal of Clinical Oncology

    303 publications · 28.7K citations

    91

    h-index

  2. Blood

    258 publications · 23.1K citations

    65

    h-index

  3. Clinical Cancer Research

    63 publications · 5.6K citations

    45

    h-index

  4. 44

    h-index

  5. PubMed

    Repository · 113 publications · 7K citations

    39

    h-index

1–5