Concepedia

Bayesian Dose Escalation

Bayesian Dose Escalation is a dose-finding methodology in clinical trial design that uses Bayesian statistical inference to sequentially update the probability of toxicity and efficacy outcomes, guiding dose escalation decisions based on accumulating data and prior knowledge.

123

Publications

7.1K

Citations

445

Authors

221

Institutions

Publications per year

2017–2026

44

Parents

Publications

123

Dose‐Finding Based on Efficacy–Toxicity Trade‐Offs

Peter F. Thall, John D. Cook · Biometrics · 2004 · 510 citations

, , +13

Some practical improvements in the continual reassessment method for phase I studies

Steven N. Goodman, Marianna Zahurak, Steven Piantadosi · Statistics in Medicine · 1995 · 474 citations

, , +11

Critical aspects of the Bayesian approach to phase I cancer trials

Beat Neuenschwander, Michael Branson, Thomas Gsponer · Statistics in Medicine · 2008 · 436 citations · Full text

, , +12

A Strategy for Dose-Finding and Safety Monitoring Based on Efficacy and Adverse Outcomes in Phase I/II Clinical Trials

Peter F. Thall, Kathy Russell · Biometrics · 1998 · 278 citations

, , +17

Bayesian Optimal Interval Design: A Simple and Well-Performing Design for Phase I Oncology Trials

Ying Yuan, Kenneth R. Hess, Susan G. Hilsenbeck et al. · Clinical Cancer Research · 2016 · 227 citations · Full text

, , +11

1–5 of 123

Authors

445

  1. YY
    Ying Yuan

    The University of Texas MD Anderson Cancer Center, United States

    18 publications · 1.6K citations

    17

    h-index

  2. PF
    Peter F. Thall

    The University of Texas MD Anderson Cancer Center, United States

    12 publications · 1.4K citations

    12

    h-index

  3. JW
    John Whitehead

    University of Reading, United Kingdom

    11 publications · 451 citations

    11

    h-index

  4. MT
    Mourad Tighiouart

    Emory University, United States

    10 publications · 393 citations

    10

    h-index

  5. AR
    André Rogatko

    Fox Chase Cancer Center, United States

    9 publications · 392 citations

    9

    h-index

1–5 of 445

Institutions

221

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    30 h-index

    89 publications

    8.1K citations

  2. Novartis (Switzerland)

    Basel, Switzerland

    10 h-index

    25 publications

    1.9K citations

  3. University of Reading

    Reading, United Kingdom

    10 h-index

    17 publications

    653 citations

  4. Lancaster University

    Lancaster, United Kingdom

    7 h-index

    12 publications

    225 citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    7 h-index

    9 publications

    195 citations

  6. Sarah Cannon

    Nashville, United States

    6 h-index

    7 publications

    149 citations

  7. Massachusetts General Hospital

    Boston, United States

    5 h-index

    7 publications

    159 citations

  8. Center for Global Development

    Washington D.C., United States

    5 h-index

    8 publications

    250 citations

1–8 of 221

Venues

  1. Statistics in Medicine

    20 publications · 1.7K citations

    19

    h-index

  2. Biometrics

    13 publications · 1.8K citations

    12

    h-index

  3. Journal of Biopharmaceutical Statistics

    JBS · 10 publications · 389 citations

    10

    h-index

  4. Pharmaceutical Statistics

    11 publications · 312 citations

    10

    h-index

  5. 10

    h-index

1–5