Concepedia

Adaptive Dose Escalation

Adaptive Dose Escalation is a dose escalation method in clinical trial design that dynamically adjusts subsequent dose levels based on accumulating patient data to optimize the balance between therapeutic efficacy and toxicological risk.

176

Publications

10.4K

Citations

1.1K

Authors

427

Institutions

Publications per year

2017–2026

62

Parents

Publications

176

Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer

Richard Pötter, Petra Georg, Johannes Dimopoulos et al. · Radiotherapy and Oncology · 2011 · 743 citations · Full text

, , +17

Cancer phase I clinical trials: efficient dose escalation with overdose control

James S. Babb, André Rogatko, Shelemyahu Zacks · Statistics in Medicine · 1998 · 621 citations

, , +17

Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer

Richard Pötter, Johannes Dimopoulos, Petra Georg et al. · Radiotherapy and Oncology · 2007 · 540 citations

, , +17

Using adaptive magnetic resonance image‐guided radiation therapy for treatment of inoperable pancreatic cancer

Soumon Rudra, Naomi Jiang, Stephen A. Rosenberg et al. · Cancer Medicine · 2019 · 345 citations · Full text

, , +15

Improved Sphincter Preservation in Low Rectal Cancer With High-Dose Preoperative Radiotherapy: The Lyon R96-02 Randomized Trial

Jean-Pierre Gérard, O. Chapet, Chantal Némoz et al. · Journal of Clinical Oncology · 2004 · 318 citations

, , +16

1–5 of 176

Authors

1.1K

  1. YY
    Ying Yuan

    The University of Texas MD Anderson Cancer Center, United States

    11 publications · 894 citations

    11

    h-index

  2. MT
    Mourad Tighiouart

    Emory University, United States

    7 publications · 205 citations

    7

    h-index

  3. AR
    André Rogatko

    Fox Chase Cancer Center, United States

    6 publications · 785 citations

    6

    h-index

  4. FM
    Frank Miller

    AstraZeneca (Sweden), Sweden

    4 publications · 182 citations

    4

    h-index

  5. YJ
    Yuan Ji

    Endeavor Health, United States

    4 publications · 64 citations

    4

    h-index

1–5 of 1.1K

Institutions

427

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    18 h-index

    45 publications

    3.5K citations

  2. Novartis (Switzerland)

    Basel, Switzerland

    8 h-index

    23 publications

    1.1K citations

  3. Memorial Sloan Kettering Cancer Center

    New York, United States

    7 h-index

    9 publications

    375 citations

  4. Roche (Switzerland)

    Basel, Switzerland

    7 h-index

    32 publications

    592 citations

  5. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    7 h-index

    23 publications

    691 citations

  6. Samueli Institute

    Alexandria, United States

    6 h-index

    15 publications

    482 citations

  7. Massachusetts General Hospital

    Boston, United States

    6 h-index

    15 publications

    911 citations

  8. University of Michigan

    Ann Arbor, United States

    6 h-index

    42 publications

    3.1K citations

1–8 of 427

Venues

  1. Statistics in Medicine

    18 publications · 1.4K citations

    17

    h-index

  2. 9

    h-index

  3. Journal of Biopharmaceutical Statistics

    JBS · 8 publications · 368 citations

    8

    h-index

  4. Radiotherapy and Oncology

    8 publications · 1.6K citations

    8

    h-index

  5. Journal of Clinical Oncology

    8 publications · 527 citations

    8

    h-index

1–5