Concepedia

Dose Selection

Dose Selection is the pharmacological decision-making process of determining the optimal therapeutic dose of a biologic or gene-based intervention in early clinical development, distinguished from related processes by its focus on establishing safety, biological activity, and exposure-response relationships to inform subsequent clinical trial phases.

2.2K

Publications

107.9K

Citations

11K

Authors

2.8K

Institutions

Publications per year

2017–2026

459

Parents

Children

Publications

2.2K

Calcitonin Gene–Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine

Jes Olesen, Hans‐Christoph Diener, Ingo W. Husstedt et al. · New England Journal of Medicine · 2004 · 1.2K citations · Full text

, , +16

Tables for Convenient Calculation of Median-Effective Dose (LD 50 or ED 50 ) and Instructions in Their Use

Carrol S. Weil · Biometrics · 1952 · 1.1K citations

, , +14

The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

Elizabeth Sconce, Tayyaba Khan, Hilary Wynne et al. · Blood · 2005 · 947 citations · Full text

, , +17

A Randomized Trial of Genotype-Guided Dosing of Warfarin

Munir Pirmohamed, Girvan Burnside, Niclas Eriksson et al. · New England Journal of Medicine · 2013 · 808 citations · Full text

, , +14

A Test for Differences between Treatment Means When Several Dose Levels are Compared with a Zero Dose Control

D. A. Williams · Biometrics · 1971 · 746 citations

, , +3

1–5 of 2.2K

Authors

11K

  1. YY
    Ying Yuan

    The University of Texas MD Anderson Cancer Center, United States

    34 publications · 2.5K citations

    24

    h-index

  2. PF
    Peter F. Thall

    The University of Texas MD Anderson Cancer Center, United States

    29 publications · 2.6K citations

    21

    h-index

  3. JO
    John O’Quigley

    Sorbonne Université, France

    22 publications · 1.1K citations

    17

    h-index

  4. SZ
    Sarah Zohar

    Inserm, France

    18 publications · 724 citations

    16

    h-index

  5. HM
    Hagop M. Kantarjian

    The University of Texas MD Anderson Cancer Center, United States

    18 publications · 1.5K citations

    15

    h-index

1–5 of 11K

Institutions

2.8K

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    56 h-index

    415 publications

    40.2K citations

  2. Inserm

    Paris, France

    32 h-index

    150 publications

    8.1K citations

  3. Sorbonne Université

    Paris, France

    24 h-index

    63 publications

    3.7K citations

  4. University of Toronto

    Toronto, Canada

    22 h-index

    74 publications

    3.5K citations

  5. University of Michigan

    Ann Arbor, United States

    22 h-index

    85 publications

    5.2K citations

  6. University of California, San Francisco

    San Francisco, United States

    22 h-index

    77 publications

    3.8K citations

  7. Memorial Sloan Kettering Cancer Center

    New York, United States

    22 h-index

    75 publications

    3.3K citations

  8. Harvard University

    Cambridge, United States

    21 h-index

    75 publications

    4.4K citations

1–8 of 2.8K

Venues

  1. 36

    h-index

  2. Biometrics

    55 publications · 7.1K citations

    35

    h-index

  3. Statistics in Medicine

    91 publications · 4.7K citations

    34

    h-index

  4. PubMed

    Repository · 98 publications · 3.9K citations

    30

    h-index

  5. Journal of Clinical Oncology

    54 publications · 2.8K citations

    29

    h-index

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