Concepedia

Pharmacodynamic Dose Selection

Pharmacodynamic Dose Selection is a methodological framework within pharmacology that determines the optimal drug dose based on the relationship between drug concentration and its biological effect, distinguishing it from pharmacokinetic approaches by focusing on the drug's physiological impact rather than its absorption, distribution, metabolism, and excretion.

27

Publications

1.2K

Citations

171

Authors

72

Institutions

Publications per year

2017–2026

6

Parents

Publications

27

Use of Preclinical Data for Selection of a Phase II/III Dose for Evernimicin and Identification of a Preclinical MIC Breakpoint

George L. Drusano, Sandra L. Preston, C. Hardalo et al. · Antimicrobial Agents and Chemotherapy · 2001 · 242 citations · Full text

, , +17

Pharmacodynamic dose effects of oral cannabis ingestion in healthy adults who infrequently use cannabis

Nicolas J. Schlienz, Tory R. Spindle, Edward J. Cone et al. · Drug and Alcohol Dependence · 2020 · 92 citations · Full text

, , +8

Use of pharmacokinetic/ pharmacodynamic modelling for starting dose selection in first‐in‐human trials of high‐risk biologics

Balaji Agoram · British Journal of Clinical Pharmacology · 2008 · 84 citations · Full text

, , +17

Pharmacokinetic and Pharmacodynamic Differences Between Two Low Dosages of Aspirin May Affect Therapeutic Outcomes

Chiara Cerletti, Giuseppe Dell Elba, Stefano Manarini et al. · Clinical Pharmacokinetics · 2003 · 75 citations

, , +12

Pharmacodynamic Dose-Response and Safety Study of Cisatracurium (51W89) in Adult Surgical Patients During N2 O-O2-Opioid Anesthesia

Jean-Yves Lepage, Jean-Marc Malinovsky, Myriam Malinge et al. · Anesthesia & Analgesia · 1996 · 68 citations

, , +16

1–5 of 27

Authors

171

  1. JL
    Jean-Yves Lepage

    Centre Hospitalier Universitaire de Nantes, France

    2 publications · 123 citations

    2

    h-index

  2. TL
    T. Lechevalier

    Institut Gustave Roussy, France

    2 publications · 123 citations

    2

    h-index

  3. CD
    Christine Dupuch

    American Academy of Ophthalmology, United States

    2 publications · 123 citations

    2

    h-index

  4. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    2 publications · 80 citations

    2

    h-index

  5. MP
    M∘ Pinaud

    Centre Hospitalier Universitaire de Nantes, France

    2 publications · 123 citations

    2

    h-index

1–5 of 171

Institutions

72

  1. University at Buffalo, State University of New York

    Buffalo, United States

    3 h-index

    9 publications

    504 citations

  2. Juniata College

    Huntingdon, United States

    2 h-index

    16 publications

    984 citations

  3. American Academy of Ophthalmology

    San Francisco, United States

    2 h-index

    16 publications

    984 citations

  4. Centre Hospitalier Universitaire de Nantes

    Nantes, France

    2 h-index

    16 publications

    984 citations

  5. Bioanalytica (Switzerland)

    Lucerne, Switzerland

    2 h-index

    6 publications

    319 citations

  6. Wellcome Trust

    London, United Kingdom

    2 h-index

    16 publications

    984 citations

  7. Dynamic Research (United States)

    Torrance, United States

    2 h-index

    2 publications

    81 citations

  8. Stanford Medicine

    Stanford, United States

    1 h-index

    1 publications

    23 citations

1–8 of 72

Venues

  1. International Journal of Pharmaceutics

    2 publications · 31 citations

    2

    h-index

  2. Journal of Pharmaceutical Sciences

    2 publications · 41 citations

    2

    h-index

  3. Anesthesia & Analgesia

    2 publications · 123 citations

    2

    h-index

  4. 2

    h-index

  5. Antimicrobial Agents and Chemotherapy

    AAC · 1 publications · 242 citations

    1

    h-index

1–5