Concepedia

Clinical pharmacology of UCN-01: Initial observations and comparison to preclinical models

Edward A. Sausville, Richard D. Lush, Donna Headlee, Adaline C. Smith, William D. Figg, Susan G. Arbuck, Adrian M. Senderowicz, Eiichi Fuse, Hiromi Tanii, Takashi Kuwabara,

Cancer Chemotherapy and Pharmacology · 1998 · 89 citations · 11 references

DOI

Concepts

References

11

Comprehensive toxicology

Choice Reviews Online · 1997 · 551 citations

UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p53

Qizhi Wang, Songqing Fan, Alan Eastman et al. · JNCI Journal of the National Cancer Institute · 1996 · 447 citations · Full text

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Enhancement of cisplatin-induced cytotoxicity by 7-hydroxystaurosporine (UCN-01), a new G2-checkpoint inhibitor.

Roderick T. Bunch, Alan Eastman · PubMed · 1996 · 221 citations

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Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models.

Shiro Akinaga, Katsushige Gomi, Makoto Morimoto et al. · PubMed · 1991 · 190 citations

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Differential inhibition of protein kinase C isozymes by UCN-01, a staurosporine analogue.

Caroline Seynaeve, Marcelo G. Kazanietz, P M Blumberg et al. · Molecular Pharmacology · 1994 · 161 citations

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