Makoto Morimoto

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

Tatsuya Tamaoki, Hisayo Nomoto, ISAMI TAKAHASHI et al. · Biochemical and Biophysical Research Communications · 1986 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +10

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C

Eiji Kobayashi, Hirofumi Nakano, Makoto Morimoto et al. · Biochemical and Biophysical Research Communications · 1989 · 1.1K citations

Life Sciences, Biochemistry, Medicinal Chemistry +9

Duocarmycin A, a new antitumor antibiotic from Streptomyces.

ISAMI TAKAHASHI, Keiichi Takahashi, Michio Ichimura et al. · The Journal of Antibiotics · 1988 · 195 citations · Full text

Medicine, Microbiology, Chemotherapy +4

Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models.

Shiro Akinaga, Katsushige Gomi, Makoto Morimoto et al. · PubMed · 1991 · 190 citations

Medicine, Oncology, Pharmacology +10

UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities.

ISAMI TAKAHASHI, Yutaka Saitoh, Mayumi Yoshida et al. · The Journal of Antibiotics · 1989 · 156 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +13