Adrian M. Senderowicz

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.

M Bubb, Adrian M. Senderowicz, Edward A. Sausville et al. · Journal of Biological Chemistry · 1994 · 818 citations · Full text

Life Sciences, Cell Biology, Pharmacology +15

Flavopiridol Inhibits P-TEFb and Blocks HIV-1 Replication

Sheng‐Hao Chao, Koh Fujinaga, Jon E. Marion et al. · Journal of Biological Chemistry · 2000 · 463 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.

Adrian M. Senderowicz, Donna Headlee, Sherman F. Stinson et al. · Journal of Clinical Oncology · 1998 · 408 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +15

Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25

Maryse Leost, Christiane Schultz, Andreas Link et al. · European Journal of Biochemistry · 2000 · 373 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.

Robert W. Robey, W Y Medina-Pérez, Kenryu Nishiyama et al. · PubMed · 2001 · 342 citations

Medicine, Oncology, Pharmacology +17