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Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death

Diogo Rodrigo Magalhães Moreira, Ana Daura Travassos de Oliveira, Paulo André Teixeira de Moraes Gomes, Carlos A. de Simone, Filipe Silva Villela, Rafaela Salgado Ferreira, Aline Caroline da Silva, Thiago André Ramos dos Santos, Maria Carolina Accioly Brelaz de Castro, Valéria Rêgo Alves Pereira,

European Journal of Medicinal Chemistry · 2014 · 64 citations · 53 references

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53

A new consensus for Trypanosoma cruzi intraspecific nomenclature: second revision meeting recommends TcI to TcVI

Bianca Zingales, Andrade Sg, D.M. Campbell et al. · Memórias do Instituto Oswaldo Cruz · 2009 · 1K citations · Full text

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Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain

Xiaohui Du, Chun Guo, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2002 · 383 citations · Full text

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Cysteine Protease Inhibitors Cure an Experimental <i>Trypanosoma cruzi</i> Infection

Juan C. Engel, Patricia S. Doyle, Ivy Hsieh et al. · The Journal of Experimental Medicine · 1998 · 383 citations · Full text

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In vitro and in vivo experimental models for drug screening and development for Chagas disease

Álvaro J. Romanha, Solange L. de Castro, Maria de Nazaré Correia Soeiro et al. · Memórias do Instituto Oswaldo Cruz · 2010 · 349 citations · Full text

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Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against <i>Plasmodium falciparum</i>, <i>Trypanosoma brucei</i>, and <i>Trypanosoma cruzi</i>

Doron C. Greenbaum, Zachary B. Mackey, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2004 · 254 citations · Full text

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