Patricia S. Doyle

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Publications

Citations

3.4K

H-Index

Active since

1957

Affiliations

University of California, San Francisco(Current)

National Institute of Allergy and Infectious Diseases

San Francisco General Hospital

National Institutes of Health

Inserm

Patricia S. Doyle is an author at University of California, San Francisco specializing in trypanosoma cruzi infection, pharmacology, and enzyme inhibition.

Publications per year

1957–2013

Publications

Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain

Xiaohui Du, Chun Guo, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2002 · 383 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Cysteine Protease Inhibitors Cure an Experimental Trypanosoma cruzi Infection

Juan C. Engel, Patricia S. Doyle, Ivy Hsieh et al. · The Journal of Experimental Medicine · 1998 · 383 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +15

Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi

Doron C. Greenbaum, Zachary B. Mackey, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2004 · 254 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A Cysteine Protease Inhibitor Cures Chagas' Disease in an Immunodeficient-Mouse Model of Infection

Patricia S. Doyle, Yuan Zhou, Juan C. Engel et al. · Antimicrobial Agents and Chemotherapy · 2007 · 187 citations · Full text

Medicine, Infectious Diseases, Pharmacology +13

Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain

Naoaki Fujii, Jeremy P. Mallari, Elizabeth Hansell et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 155 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

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