Patricia S. Doyle

Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain

Xiaohui Du, Chun Guo, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2002 · 379 citations · Full text

Bioorganic Chemistry, Biochemistry, Antiparasitic Agent +14

Cysteine Protease Inhibitors Cure an Experimental <i>Trypanosoma cruzi</i> Infection

Juan C. Engel, Patricia S. Doyle, Ivy Hsieh et al. · The Journal of Experimental Medicine · 1998 · 378 citations · Full text

Trypanosoma Cruzi, Antiparasitic Agent, Medicine +10

Synthesis and Structure−Activity Relationships of Parasiticidal Thiosemicarbazone Cysteine Protease Inhibitors against <i>Plasmodium falciparum</i>, <i>Trypanosoma brucei</i>, and <i>Trypanosoma cruzi</i>

Doron C. Greenbaum, Zachary B. Mackey, Elizabeth Hansell et al. · Journal of Medicinal Chemistry · 2004 · 249 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Plasmodium Falciparum +15

A Cysteine Protease Inhibitor Cures Chagas' Disease in an Immunodeficient-Mouse Model of Infection

Patricia S. Doyle, Yuan Zhou, Juan C. Engel et al. · Antimicrobial Agents and Chemotherapy · 2007 · 185 citations · Full text

Laboratory Immunology, Antiparasitic Agent, Immunodeficiencies +20

Metal compounds for the treatment of parasitic diseases

Simon P. Fricker, Renée Mosi, Beth R. Cameron et al. · Journal of Inorganic Biochemistry · 2008 · 152 citations

Medicinal Chemistry, Antiparasitic Agent, Medicine +7