Filipe Silva Villela

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio et al. · PLoS Pathogens · 2016 · 448 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death

Diogo Rodrigo Magalhães Moreira, Ana Daura Travassos de Oliveira, Paulo André Teixeira de Moraes Gomes et al. · European Journal of Medicinal Chemistry · 2014 · 64 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +17

Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain

José Wanderlan Pontes Espíndola, Marcos Veríssimo de Oliveira Cardoso, Gevânio Bezerra de Oliveira Filho et al. · European Journal of Medicinal Chemistry · 2015 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Zirconium catalyzed synthesis of 2-arylidene Indan-1,3-diones and evaluation of their inhibitory activity against NS2B-NS3 WNV protease

Ana Flávia C. da S. Oliveira, Ana Paula Martins de Souza, André Silva de Oliveira et al. · European Journal of Medicinal Chemistry · 2018 · 29 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Discovery and characterization of trypanocidal cysteine protease inhibitors from the ‘malaria box’

Glaécia A. N. Pereira, Elany B. da Silva, Saulo Fehelberg Pinto Braga et al. · European Journal of Medicinal Chemistry · 2019 · 24 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +14