Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Clotilde Théry, Kenneth W. Witwer, Elena Aïkawa, +377

Journal of Extracellular Vesicles

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

Robert M. Grant, Javier R. Lama, Peter L. Anderson, +32

New England Journal of Medicine

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

Douglas E. V. Pires, Tom L. Blundell, David B. Ascher

Journal of Medicinal Chemistry

Central Admet PropertiesPkcsm PerformsEngineeringPredictive ToxicologyPhysiologically-based Pharmacokinetic Modeling +13

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹

Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, +1267

Autophagy

The Brazilian health system: history, advances, and challenges

Jairnilson Silva Paim, Cláudia Travassos, C.M.V.B. Almeida, +2

The Lancet

Health SystemsHealth System AnalysisComparative Health SystemsBrazilian Health SystemHealth Policy +3

Zika Virus Infection in Pregnant Women in Rio de Janeiro

Patrícia Brasil, José Paulo Pereira, Maria Elisabeth Lopes Moreira, +29

New England Journal of Medicine

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

Raquel Viana, Sikhulile Moyo, Daniel G. Amoako, +94

Nature

Detection of a SARS-CoV-2 variant of concern in South Africa

Houriiyah Tegally, Eduan Wilkinson, Marta Giovanetti, +44

Nature

RadarVaccinationEngineeringVirus EpidemiologyViral Diagnostics +8

A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium

Luciano Andrade Moreira, Iñaki Iturbe‐Ormaetxe, J. Jeffery, +14

Cell

Vector-borne PathogenWolbachia SymbiontInsect VirusMalariaEntomology +8

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

Zhibin Zhang, Ying Zhang, Shiyu Xia, +11

Nature

Tumor BiologyGasdermin EImmunologyTumor ImmunityTumor Suppressor +5