Concepedia

Conformational Specificity

Conformational Specificity is the property of a biomolecular structure that distinguishes its functionally relevant three-dimensional folding state from other possible conformations by virtue of its precise spatial arrangement and energetic stability under physiological conditions.

203

Publications

10.5K

Citations

963

Authors

326

Institutions

Publications per year

2017–2026

23

Parents

Publications

203

Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau

Gregory A. Jicha, Robert Bowser, Imrana G. Kazam et al. · Journal of Neuroscience Research · 1997 · 565 citations

, , +17

Salt bridges: Geometrically specific, designable interactions

Jason E. Donald, Daniel W. Kulp, William F. DeGrado · Proteins Structure Function and Bioinformatics · 2010 · 402 citations · Full text

, , +15

Are buried salt bridges important for protein stability and conformational specificity?

Carey D. Waldburger, Joel F. Schildbach, Robert T. Sauer · Nature Structural & Molecular Biology · 1995 · 324 citations

, , +14

Resveratrol Selectively Remodels Soluble Oligomers and Fibrils of Amyloid Aβ into Off-pathway Conformers

Ali Reza A. Ladiwala, Jason Lin, Shyam Sundhar Bale et al. · Journal of Biological Chemistry · 2010 · 296 citations · Full text

, , +17

The Discovery of Capsazepine, the First Competitive Antagonist of the Sensory Neuron Excitants Capsaicin and Resiniferatoxin

Christopher Walpole, Stuart Bevan, G. Bovermann et al. · Journal of Medicinal Chemistry · 1994 · 210 citations

, , +16

1–5 of 203

Authors

963

  1. PM
    Peter M. Tessier

    Rensselaer Polytechnic Institute, United States

    3 publications · 525 citations

    3

    h-index

  2. FA
    F. A. Anderer

    Friedrich Miescher Laboratory, Germany

    3 publications · 40 citations

    3

    h-index

  3. NS
    Nathaniel S. Finney

    University of California San Diego, United States

    3 publications · 330 citations

    3

    h-index

  4. JC
    Jonathan Clayden

    University of Manchester, United Kingdom

    3 publications · 249 citations

    3

    h-index

  5. JV
    Jesse V. Mello

    University of California San Diego, United States

    2 publications · 192 citations

    2

    h-index

1–5 of 963

Institutions

326

  1. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    28 publications

    939 citations

  2. University of California San Diego

    San Diego, United States

    5 h-index

    17 publications

    1.1K citations

  3. Max Planck Society

    Munich, Germany

    4 h-index

    7 publications

    170 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    21 publications

    2.1K citations

  5. Harvard University

    Cambridge, United States

    3 h-index

    13 publications

    285 citations

  6. University of Wisconsin–Madison

    Madison, United States

    3 h-index

    17 publications

    904 citations

  7. At Bristol

    Bristol, United Kingdom

    3 h-index

    8 publications

    535 citations

  8. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    15 publications

    1.9K citations

1–8 of 326

Venues

  1. Journal of Medicinal Chemistry

    22 publications · 1.2K citations

    18

    h-index

  2. Biochemistry

    15 publications · 801 citations

    15

    h-index

  3. Journal of the American Chemical Society

    JACS · 12 publications · 758 citations

    12

    h-index

  4. Journal of Biological Chemistry

    JBC · 7 publications · 685 citations

    7

    h-index

  5. Tetrahedron Letters

    6 publications · 230 citations

    6

    h-index

1–5