Christopher Walpole

Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin

Stuart Bevan, Sandeep S Hothi, Glyn A. Hughes et al. · British Journal of Pharmacology · 1992 · 581 citations · Full text

Competitive Antagonism, Neurotransmitter, Competitive Antagonist +18

The Discovery of Capsazepine, the First Competitive Antagonist of the Sensory Neuron Excitants Capsaicin and Resiniferatoxin

Christopher Walpole, Stuart Bevan, G. Bovermann et al. · Journal of Medicinal Chemistry · 1994 · 208 citations

Pain Medicine, Neurotransmitter, Anesthetic Mechanism +17

Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 1. The aromatic "A-region"

Christopher Walpole, Roger Wrigglesworth, Stuart Bevan et al. · Journal of Medicinal Chemistry · 1993 · 162 citations · Full text

New Diarylmethylpiperazines as Potent and Selective Nonpeptidic δ Opioid Receptor Agonists with Increased In Vitro Metabolic Stability

Niklas Plobeck, Daniel Delorme, Zhongyong Wei et al. · Journal of Medicinal Chemistry · 2000 · 115 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +15

Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 3. The hydrophobic side-chain "C-region"

Christopher Walpole, Roger Wrigglesworth, Stuart Bevan et al. · Journal of Medicinal Chemistry · 1993 · 110 citations · Full text

Pharmaceutical Science, Neuropeptides, Pain Medicine +18