Glyn A. Hughes

Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin

Stuart Bevan, Sandeep S Hothi, Glyn A. Hughes et al. · British Journal of Pharmacology · 1992 · 581 citations · Full text

Competitive Antagonism, Neurotransmitter, Competitive Antagonist +18

The Discovery of Capsazepine, the First Competitive Antagonist of the Sensory Neuron Excitants Capsaicin and Resiniferatoxin

Christopher Walpole, Stuart Bevan, G. Bovermann et al. · Journal of Medicinal Chemistry · 1994 · 208 citations

Pain Medicine, Neurotransmitter, Anesthetic Mechanism +17

Bradyzide, a potent non‐peptide B₂ bradykinin receptor antagonist with long‐lasting oral activity in animal models of inflammatory hyperalgesia

Gillian M. Burgess, Martin Perkins, H P Rang et al. · British Journal of Pharmacology · 2000 · 104 citations · Full text

2-Nitrophenylcarbamoyl-(<i>S</i>)-prolyl-(<i>S</i>)-3-(2-naphthyl)alanyl-<i>N</i>-benzyl-<i>N</i>- methylamide (SDZ NKT 343), a Potent Human NK₁ Tachykinin Receptor Antagonist with Good Oral Analgesic Activity in Chronic Pain Models

Christopher Walpole, Sun Young Ko, Michael C. Brown et al. · Journal of Medicinal Chemistry · 1998 · 65 citations · Full text

Pain Disorders, Pain Medicine, Benzylthiourea Substituent +23

Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents:  Structure−Activity Studies. 4. Potent, Orally Active Analgesics

Roger Wrigglesworth, Christopher Walpole, Stuart Bevan et al. · Journal of Medicinal Chemistry · 1996 · 63 citations · Full text

Pharmaceutical Science, Pain Medicine, Active Analgesics +18