Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation - Concepedia

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Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation

DOI Full Paper Access

60

Citations

16

References

2006

Year

Shaun R. Stauffer, Matthew G. Stanton, Alison R. Gregro, Melissa A. Steinbeiser, Jennifer R. Shaffer, Philippe G. Nantermet, James C. Barrow, Kenneth E. Rittle, Dennis Collusi, Amy S. Espeseth,

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryIsonicotinamide Bace-1 InhibitorsNatural SciencesMedicineRational Drug DesignMechanism Of ActionMolecular BiologyConformational StudyChemical BiologyMolecular DockingMolecular ModelingDrug Discovery

References

	Year	Citations

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