Matthew G. Stanton

A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates

Staci Sabnis, E. Sathyajith Kumarasinghe, Timothy Salerno et al. · Molecular Therapy · 2018 · 794 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +16

Impact of mRNA chemistry and manufacturing process on innate immune activation

Jennifer Nelson, Elizabeth W. Sorensen, Shrutika Mintri et al. · Science Advances · 2020 · 341 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)

Joey L. Methot, Prasun K. Chakravarty, Mélissa Chénard et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 187 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +10

5′‐(<i>E</i>)‐Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA–GalNAc Conjugates

Rubina Parmar, Jennifer L. S. Willoughby, Jingxuan Liu et al. · ChemBioChem · 2016 · 137 citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Asymmetric Total Synthesis of (−)-Laulimalide:  Exploiting the Asymmetric Glycolate Alkylation Reaction

Michael T. Crimmins, Matthew G. Stanton, Shawn P. Allwein · Journal of the American Chemical Society · 2002 · 75 citations

Pharmacy, Chemistry, Medicinal Chemistry +13