Publication | Open Access

The inefficiency of incisions of ecteinascidin 743–DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent

Ecteinascidin 743–DnaNucleic Acid ChemistryOligonucleotideMolecular BiologyPathologyUvrabc NucleaseMolecular OncologyDna AdductsAnti-cancer AgentMedicineCancer Research