David J. Bearss

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c- <i>MYC</i> transcription

Adam Siddiqui-Jain, Cory L. Grand, David J. Bearss et al. · Proceedings of the National Academy of Sciences · 2002 · 2.2K citations

Life Sciences, Genetics, Molecular Biology +17

An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Lauren A. Byers, Lixia Diao, Jing Wang et al. · Clinical Cancer Research · 2012 · 1.1K citations · Full text

Medicine, Oncology, Pharmacology +17

Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3

Wen‐Ming Yang, Carla Inouye, Yingying Zeng et al. · Proceedings of the National Academy of Sciences · 1996 · 543 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray.

Haiyong Han, David J. Bearss, L. Walden Browne et al. · PubMed · 2002 · 379 citations

Life Sciences, Molecular Biology, Oncology +15

The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo.

Cory L. Grand, Haiyong Han, Rubén M. Muñoz et al. · PubMed · 2002 · 370 citations

Medicine, Molecular Biology, Oncology +17