Lauren A. Byers

An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Lauren A. Byers, Lixia Diao, Jing Wang et al. · Clinical Cancer Research · 2012 · 1.1K citations · Full text

Medicine, Oncology, Pharmacology +17

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

Limo Chen, Don L. Gibbons, Sangeeta Goswami et al. · Nature Communications · 2014 · 995 citations · Full text

Medicine, Cancer Biology, Oncology +16

Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

Carl M. Gay, C. Allison Stewart, Elizabeth M. Park et al. · Cancer Cell · 2021 · 932 citations · Full text

Medicine, Cancer Biology, Molecular Biology +10

Co-occurring Genomic Alterations Define Major Subsets of <i>KRAS</i> -Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

Ferdinandos Skoulidis, Lauren A. Byers, Lixia Diao et al. · Cancer Discovery · 2015 · 916 citations · Full text

Medicine, Immunology, Oncology +17

Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer

Triparna Sen, B. Leticia Rodriguez, Limo Chen et al. · Cancer Discovery · 2019 · 881 citations · Full text

Life Sciences, Immunology, Oncology +17