Adam Siddiqui-Jain

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c- <i>MYC</i> transcription

Adam Siddiqui-Jain, Cory L. Grand, David J. Bearss et al. · Proceedings of the National Academy of Sciences · 2002 · 2.2K citations · Full text

Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor Growth

Denis Drygin, Amy Lin, Josh Bliesath et al. · Cancer Research · 2010 · 610 citations

Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis

Denis Drygin, Adam Siddiqui-Jain, Sean O’Brien et al. · Cancer Research · 2009 · 586 citations

Oncogenic Agent, Medicine, Pharmacology +15

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

Adam Siddiqui-Jain, Denis Drygin, Nicole Streiner et al. · Cancer Research · 2010 · 501 citations

The Dynamic Character of the G-Quadruplex Element in the c-MYC Promoter and Modification by TMPyP4

Jeyaprakashnarayanan Seenisamy, Evonne M. Rezler, Tiffanie J. Powell et al. · Journal of the American Chemical Society · 2004 · 382 citations

Molecular Regulation, G-quadruplex Element, Molecular Biology +16