Maha Zewail‐Foote

Ecteinascidin 743:  A Minor Groove Alkylator That Bends DNA toward the Major Groove

Maha Zewail‐Foote, Laurence H. Hurley · Journal of Medicinal Chemistry · 1999 · 203 citations

Molecular Biology, Et 743, Tumor Biology +18

Differential Rates of Reversibility of Ecteinascidin 743−DNA Covalent Adducts from Different Sequences Lead to Migration to Favored Bonding Sites

Maha Zewail‐Foote, Laurence H. Hurley · Journal of the American Chemical Society · 2001 · 78 citations

The inefficiency of incisions of ecteinascidin 743–DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent

Maha Zewail‐Foote, Ven-Shun Li, Harold Kohn et al. · Chemistry & Biology · 2001 · 74 citations · Full text

Ecteinascidin 743–Dna, Nucleic Acid Chemistry, Oligonucleotide +8

A sequence-specific threading tetra-intercalator with an extremely slow dissociation rate constant

Garen G. Holman, Maha Zewail‐Foote, Amy Smith et al. · Nature Chemistry · 2011 · 65 citations

Engineering, Physics

Alternative DNA structure formation in the mutagenic human c-MYC promoter

Imee Marie A. del Mundo, Maha Zewail‐Foote, Sean M. Kerwin et al. · Nucleic Acids Research · 2017 · 50 citations · Full text

Genetic Instability, Genetics, Molecular Biology +18