Concepedia

Structure-based design of non-peptidic pyridone aldehydes as inhibitors of interleukin-1β converting enzyme

Julian M.C. Golec, Michael D. Mullican, Mark A. Murcko, Keith P. Wilson, David P. Kay, Stuart Jones, Robert Murdoch, Guy W. Bemis, Scott A. Raybuck, Yu-Ping Luong,

Bioorganic & Medicinal Chemistry Letters · 1997 · 25 citations · 26 references

DOI

Concepts

References

26

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

, , +12

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

Dyana K. Dalton, Sharon Pitts-Meek, Satish Keshav et al. · Science · 1993 · 1.7K citations

, , +17

Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme

Keisuke Kuida, Judith A. Lippke, George Ku et al. · Science · 1995 · 1.6K citations

, , +16

Immune Response in Mice that Lack the Interferon-γ Receptor

Sui Huang, Wiljan Hendriks, Alana Althage et al. · Science · 1993 · 1.6K citations · Full text

, , +17

Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock

Ping Li, Hamish Allen, Subhashis Banerjee et al. · Cell · 1995 · 1.4K citations · Full text

, , +13