Stuart Jones

First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib

Dominic I. James, Kate M. Smith, Allan M. Jordan et al. · ACS Chemical Biology · 2016 · 148 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

PRO_SELECT:  Combining Structure-Based Drug Design and Array-Based Chemistry for Rapid Lead Discovery. 2. The Development of a Series of Highly Potent and Selective Factor Xa Inhibitors

John W. Liebeschuetz, Stuart Jones, Phillip J. Morgan et al. · Journal of Medicinal Chemistry · 2002 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Total Synthesis of an Oxepine Natural Product, (±)-Janoxepin

Richard G. Doveston, René R. E. Steendam, Stuart Jones et al. · Organic Letters · 2012 · 47 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity

Rebecca Newton, Katherine A. Bowler, Emily M. Burns et al. · European Journal of Medicinal Chemistry · 2016 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells

Stuart Jones, Jonathan Ahmet, Kelly Ayton et al. · Journal of Medicinal Chemistry · 2016 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17