Kate M. Smith

Procalcitonin Algorithm in Critically Ill Adults with Undifferentiated Infection or Suspected Sepsis. A Randomized Controlled Trial

Yahya Shehabi, Martin Štěrba, Peter Garrett et al. · American Journal of Respiratory and Critical Care Medicine · 2014 · 194 citations

First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib

Dominic I. James, Kate M. Smith, Allan M. Jordan et al. · ACS Chemical Biology · 2016 · 137 citations · Full text

Biochemistry, Medicine, Natural Sciences +13

DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors

Nisha Pillay, Anthony Tighe, Louisa Nelson et al. · Cancer Cell · 2019 · 128 citations · Full text

Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase

Polly Gravells, Emma K. Grant, Kate M. Smith et al. · DNA repair · 2017 · 84 citations · Full text

Dna Damage, Apoptosis, Glycobiology +16

Toxoflavins and Deazaflavins as the First Reported Selective Small Molecule Inhibitors of Tyrosyl-DNA Phosphodiesterase II

Ali Raoof, Paul Depledge, Niall M. Hamilton et al. · Journal of Medicinal Chemistry · 2013 · 61 citations · Full text