Dominic I. James

AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with <i>In vitro</i> and <i>In vivo</i> Antitumor Activity

Christine M. Chresta, Barry R. Davies, Ian Hickson et al. · Cancer Research · 2009 · 790 citations · Full text

Mtorc2 Substrate Akt, Cell Death, Pharmacotherapy +21

hFis1, a Novel Component of the Mammalian Mitochondrial Fission Machinery

Dominic I. James, Philippe A. Parone, Yves Mattenberger et al. · Journal of Biological Chemistry · 2003 · 635 citations · Full text

Mitochondrial bioenergetics and structural network organization

Giovanni Bénard, Nadège Bellancé, Dominic I. James et al. · Journal of Cell Science · 2007 · 609 citations · Full text

Molecular Biology, Mitochondrial Biology, Mitochondrial Fission +20

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA

Philippe A. Parone, Sandrine Da Cruz, Daniel Tondera et al. · PLoS ONE · 2008 · 405 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Genetics +18

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Ewa Gogola, Alexandra A. Duarte, Julian R. de Ruiter et al. · Cancer Cell · 2018 · 379 citations · Full text

Parg Restores Parylation, Selective Loss, Medicine +4