Julian R. de Ruiter

Replication fork stability confers chemoresistance in BRCA-deficient cells

Arnab Ray Chaudhuri, Elsa Callén, Xia Ding et al. · Nature · 2016 · 932 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Ewa Gogola, Alexandra A. Duarte, Julian R. de Ruiter et al. · Cancer Cell · 2018 · 385 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden, Dennis Wang, Mike J. Mason et al. · Nature Communications · 2019 · 363 citations · Full text

Medicine, Oncology, Pharmacology +16

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

Roelof J.C. Kluin, Kristel Kemper, Thomas Kuilman et al. · BMC Bioinformatics · 2018 · 171 citations · Full text

Life Sciences, Bioinformatics, Oncology +17

BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance

Alexandra A. Duarte, Ewa Gogola, Norman Sachs et al. · Nature Methods · 2017 · 152 citations · Full text

Medicine, Cancer Biology, Oncology +14