Concepedia

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

Christian Wiesmann, Kenneth J. Katschke, Jianping Yin, Karim Y. Helmy, Micah Steffek, Wayne J. Fairbrother, Scott A. McCallum, Lizette Embuscado, Laura DeForge, Philip E. Hass,

Nature · 2006 · 242 citations · 18 references

DOI

Concepts

References

18

CRIg: A Macrophage Complement Receptor Required for Phagocytosis of Circulating Pathogens

Karim Y. Helmy, Kenneth J. Katschke, Nick N. Gorgani et al. · Cell · 2006 · 611 citations · Full text

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Structures of complement component C3 provide insights into the function and evolution of immunity

B.J.C. Janssen, Eric G. Huizinga, H.C.A. Raaijmakers et al. · Nature · 2005 · 548 citations · Full text

, , +12

Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3.

Michael K. Pangburn, Robert D. Schreiber, Hans J. Müller‐Eberhard · The Journal of Experimental Medicine · 1981 · 443 citations · Full text

, , +10

Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement.

Michael K. Pangburn, Hans J. Müller‐Eberhard · The Journal of Experimental Medicine · 1980 · 336 citations · Full text

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Functional analysis of the classical, alternative, and MBL pathways of the complement system: standardization and validation of a simple ELISA

Marc A. Seelen, A. Roos, Jörgen Wieslander et al. · Journal of Immunological Methods · 2004 · 290 citations

, , +14