Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability

A Diarylquinoline Drug Active on the ATP Synthase of <i>Mycobacterium tuberculosis</i>

Koen Andries, Peter Verhasselt, Jérôme Guillemont et al. · Science · 2004 · 2.2K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa

Neel R. Gandhi, Anthony P. Moll, A. Willem Sturm et al. · The Lancet · 2006 · 1.7K citations

Public Health, Infectious Diseases, Microbiology +16

A Novel In Vitro Multiple-Stress Dormancy Model for Mycobacterium tuberculosis Generates a Lipid-Loaded, Drug-Tolerant, Dormant Pathogen

Chirajyoti Deb, Chang‐Muk Lee, Vinod S. Dubey et al. · PLoS ONE · 2009 · 446 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

Anna E. Grzegorzewicz, Hà Phạm, Vijay A. K. B. Gundi et al. · Nature Chemical Biology · 2012 · 441 citations

Life Sciences, Biochemistry, Microbiology +11

Contribution of the<i>Mycobacterium tuberculosis</i>MmpL Protein Family to Virulence and Drug Resistance

Pilar Domenech, Michael B. Reed, Clifton E. Barry · Infection and Immunity · 2005 · 361 citations

Life Sciences, Microbiology, Molecular Biology +16