Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

Anna E. Grzegorzewicz, Hà Phạm, Vijay A. K. B. Gundi, +13

Nature Chemical Biology

Pulmonary TuberculosisBiochemistryMembrane TransportTuberculosisMicrobiology +4

High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors

Thierry Christophe, Mary Jackson, Hee Kyoung Jeon, +25

PLoS Pathogens

Antimicrobial ChemotherapyDrug ResistanceMedicinal ChemistryM. TuberculosisMycobacterium Tuberculosis +19

Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression

Monika Linke, Hà Phạm, Karl Katholnig, +19

Nature Immunology

InflammationCell RegulationGranulocyteAutophagyImmunology +10

STAT5BN642H is a driver mutation for T cell neoplasia

Hà Phạm, Barbara Maurer, Michaela Prchal‐Murphy, +21

Journal of Clinical Investigation

Aurora Kinase GenesSomatic VariantGenetic DisorderMedicineMalignant Blood Disorder +11

Structural and functional consequences of the STAT5BN642H driver mutation

Elvin D. de Araujo, Fettah Erdogan, Heidi A. Neubauer, +21

Nature Communications

Lipoarabinomannan of <i>Mycobacterium</i> : Mannose capping by a multifunctional terminal mannosyltransferase

Andrés Obregón‐Henao, Hà Phạm, Delphi Chatterjee, +2

Proceedings of the National Academy of Sciences

Proteinlipid InteractionBacteriologyMolecular BiologyMicrobial PhysiologyLam Variants +17

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

Marı́a de la Paz Santangelo, Petra Gest, Marcelo E. Guerin, +13

Journal of Biological Chemistry

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Johannes Schmoellerl, Inês Amorim Monteiro Barbosa, Thomas Eder, +24

Blood

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

Alexander Swoboda, Robert Soukup, Oliver Eckel, +24

Oncogene

Cancer ResearchSignal TransductionSignaling PathwayCell RegulationMedicine +10

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies

Patricia Freund, Marc A. Kerenyi, Marlene Hager, +11

Leukemia