Anne J. Lenaerts

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis

Kévin Pethe, Pablo Bifani, Jichan Jang et al. · Nature Medicine · 2013 · 595 citations · Full text

Medicinal Chemistry, Potent Clinical Candidate, Pulmonary Tuberculosis +7

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

Anna E. Grzegorzewicz, Hà Phạm, Vijay A. K. B. Gundi et al. · Nature Chemical Biology · 2012 · 434 citations

Pulmonary Tuberculosis, Biochemistry, Membrane Transport +6

Preclinical Testing of the Nitroimidazopyran PA-824 for Activity against <i>Mycobacterium tuberculosis</i> in a Series of In Vitro and In Vivo Models

Anne J. Lenaerts, Veronica Gruppo, Karen S. Marietta et al. · Antimicrobial Agents and Chemotherapy · 2005 · 304 citations · Full text

Evaluation of a Mouse Model of Necrotic Granuloma Formation Using C3HeB/FeJ Mice for Testing of Drugs against Mycobacterium tuberculosis

Emily Driver, Gavin J. Ryan, Donald R. Hoff et al. · Antimicrobial Agents and Chemotherapy · 2012 · 270 citations

Necrotic Lesions, Medical Microbiology, Pulmonary Tuberculosis +12

Location of Persisting Mycobacteria in a Guinea Pig Model of Tuberculosis Revealed by R207910

Anne J. Lenaerts, Donald R. Hoff, Sahar Aly et al. · Antimicrobial Agents and Chemotherapy · 2007 · 258 citations · Full text