Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide–MHC class II chimera

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature · 1997 · 3.6K citations

Life Sciences, Immunology, Pathology +12

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse.

Deborah J. Lenschow, Shu‐Chuan Ho, Husain Sattar et al. · The Journal of Experimental Medicine · 1995 · 587 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.

Jide Tian, Mark A. Atkinson, Michael Clare‐Salzler et al. · The Journal of Experimental Medicine · 1996 · 426 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23).

Dylan Daniel, Dale R. Wegmann · Proceedings of the National Academy of Sciences · 1996 · 409 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.

Dana Elias, Tamara Reshef, Ohad S. Birk et al. · Proceedings of the National Academy of Sciences · 1991 · 375 citations

Life Sciences, Immunology, Pathobiology +17