Concepedia

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

Marc Veldhoen, Catherine Uyttenhove, Jacques Van Snick, Helena Helmby, Astrid M. Westendorf, Jan Buer, Bruno Martin, Christoph Wilhelm, Brigitta Stockinger

Nature Immunology · 2008 · 1.2K citations · 27 references

DOI

Concepts

References

27

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Timothy R. Mosmann, Holly Cherwinski, M W Bond et al. · The Journal of Immunology · 1986 · 7.5K citations

, , +16

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

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Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology · 2005 · 4.7K citations

, , +17

TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology

Kristian Sass Bak‐Jensen, Yi Chen, Cristina M. Tato et al. · Nature Immunology · 2007 · 1.5K citations

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Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease

Leonid Gorelik, Richard A. Flavell · Immunity · 2000 · 972 citations · Full text

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