Concepedia

IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells

Cheryl Sweeney, Róisín Lonergan, Sharee A. Basdeo, Katie Kinsella, Lara S. Dungan, Sarah Higgins, Patrick J. Kelly, Lisa Costelloe, Niall Tubridy, Kingston H. G. Mills,

Brain Behavior and Immunity · 2011 · 132 citations · 43 references

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43

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text

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Transforming growth factor-β induces development of the TH17 lineage

Paul R. Mangan, Laurie E. Harrington, Darrell B. O’Quinn et al. · Nature · 2006 · 3K citations

, , +11

Development, cytokine profile and function of human interleukin 17–producing helper T cells

Nicholas J. Wilson, Katia Boniface, Jason R. Chan et al. · Nature Immunology · 2007 · 2K citations

, , +14

Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells

Eva V. Acosta Rodríguez, Giorgio Napolitani, Antonio Lanzavecchia et al. · Nature Immunology · 2007 · 1.8K citations

, , +16

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

Christopher Lock, G Hermans, Rosetta Pedotti et al. · Nature Medicine · 2002 · 1.7K citations

, , +16