Synthesis and evaluation of double bond substituted combretastatins

Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4

George R. Pettit, Sheo B. Singh, Ernest Hamel et al. · Cellular and Molecular Life Sciences · 1989 · 783 citations

Natural Sciences, Molecular Biology, Cytoskeleton +8

Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature.

G. Dark, S A Hill, Vivien E. Prise et al. · PubMed · 1997 · 624 citations

Vascular Shutdown, Tumor Biology, Oncology +16

Antineoplastic Agents. 291. Isolation and Synthesis of Combretastatins A-4, A-5, and A-6

George R. Pettit, Sheo B. Singh, Michael R. Boyd et al. · Journal of Medicinal Chemistry · 1995 · 389 citations

Medicinal Chemistry, Biochemistry, Antiparasitic Agent +15

Potent antimitotic and cell growth inhibitory properties of substituted chalcones

Sylvie Ducki, Richard Forrest, John A. Hadfield et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 365 citations · Full text

Medicinal Chemistry, Natural Sciences, Medicine +6

Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization

Mark Cushman, Dhanapalan Nagarathnam, Dhanushya Gopal et al. · Journal of Medicinal Chemistry · 1991 · 297 citations · Full text