Keira Gaukroger

Novel Syntheses of Cis and Trans Isomers of Combretastatin A-4

Keira Gaukroger, John A. Hadfield, Lucy A. Hepworth et al. · The Journal of Organic Chemistry · 2001 · 175 citations · Full text

Molecular Biology, Organic Chemistry, Chemistry +16

Structural requirements for the interaction of combretastatins with tubulin: how important is the trimethoxy unit?

Keira Gaukroger, John A. Hadfield, Nicholas J. Lawrence et al. · Organic & Biomolecular Chemistry · 2003 · 127 citations · Full text

Protein Tubulin, Bioorganic Chemistry, Molecular Biology +17

Structure–Activity Relationships of C-17 Cyano-Substituted Estratrienes as Anticancer Agents

Mathew P. Leese, Fabrice Jourdan, Keira Gaukroger et al. · Journal of Medicinal Chemistry · 2008 · 52 citations · Full text

Synthesis and evaluation of double bond substituted combretastatins

John A. Hadfield, Keira Gaukroger, Nicholas Hirst et al. · European Journal of Medicinal Chemistry · 2005 · 37 citations · Full text

Double Bond, Synthetic Chemistry, Chemistry +1

The effects of 2-methoxyoestrogen sulphamates on the in vitro and in vivo proliferation of breast cancer cells

Toshiaki Utsumi, Mathew P. Leese, Surinder K. Chander et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2005 · 30 citations

Breast Oncology, Medicine, Breast Cancer Cells +8