Karyotypic abnormalities create discordance of germline genotype and cancer cell phenotypes

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Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency: Genetic Basis for Azathioprine and Mercaptopurine Intolerance

Charles R. Yates, Eugene Y. Krynetski, Thrina Loennechen et al. · Annals of Internal Medicine · 1997 · 763 citations

Life Sciences, Genetics, Pharmacology +13

Rationale and design of Total Therapy Study XV for newly diagnosed childhood acute lymphoblastic leukemia.

Ching‐Hon Pui, M V Relling, J T Sandlund et al. · PubMed · 2004 · 366 citations

Medicine, Oncology, Pediatrics +9

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.

Hung-Liang Tai, Eugene Y. Krynetski, Charles R. Yates et al. · PubMed · 1996 · 320 citations

Life Sciences, Genetics, Molecular Genetics +15

A Polymorphism (80G->A) in the Reduced Folate Carrier Gene and Its Associations with Folate Status and Homocysteinemia

Abalo Chango, Nathalie Emery‐Fillon, G. Potier de Courcy et al. · Molecular Genetics and Metabolism · 2000 · 301 citations

Life Sciences, Genetics, Molecular Genetics +13