Concepedia

Germline Predisposition

Germline Predisposition is a genetic susceptibility to pediatric cancer arising from inherited pathogenic variants in germ cells that confer an increased risk of tumor development during childhood.

1.8K

Publications

113.9K

Citations

15K

Authors

3.1K

Institutions

Publications per year

2017–2026

610

Parents

Publications

1.8K

The landscape of genomic alterations across childhood cancers

Susanne Gröbner, Barbara C. Worst, Joachim Weischenfeldt et al. · Nature · 2018 · 1.6K citations · Full text

, , +17

Germline Mutations in Predisposition Genes in Pediatric Cancer

Jinghui Zhang, Michael F. Walsh, Gang Wu et al. · New England Journal of Medicine · 2015 · 1.4K citations · Full text

, , +17

INFANTILE AUTISM: A GENETIC STUDY OF 21 TWIN PAIRS

Susan E. Folstein, Michael Rutter · Journal of Child Psychology and Psychiatry · 1977 · 1.3K citations

, , +14

Germline BAP1 mutations predispose to malignant mesothelioma

Joseph R. Testa, Mitchell Cheung, Jianming Pei et al. · Nature Genetics · 2011 · 1.1K citations · Full text

, , +12

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Claire Palles, Jean‐Baptiste Cazier, Kimberley Howarth et al. · Nature Genetics · 2012 · 1K citations · Full text

, , +14

1–5 of 1.8K

Authors

15K

  1. KE
    Kim E. Nichols

    St. Jude Children's Research Hospital, United States

    26 publications · 2.9K citations

    19

    h-index

  2. ZK
    Zsofia K. Stadler

    Memorial Sloan Kettering Cancer Center, United States

    20 publications · 1.3K citations

    18

    h-index

  3. DG
    D. Gareth Evans

    University of Manchester, United Kingdom

    20 publications · 2.5K citations

    18

    h-index

  4. KO
    Kenneth Offit

    Memorial Sloan Kettering Cancer Center, United States

    21 publications · 1.6K citations

    17

    h-index

  5. ME
    Mark E. Robson

    Memorial Sloan Kettering Cancer Center, United States

    20 publications · 2.5K citations

    17

    h-index

1–5 of 15K

Institutions

3.1K

  1. Inserm

    Paris, France

    41 h-index

    373 publications

    41K citations

  2. National Cancer Institute

    Bethesda, United States

    39 h-index

    420 publications

    27K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    36 h-index

    199 publications

    13.3K citations

  4. Mayo Clinic

    Rochester, United States

    35 h-index

    199 publications

    22.7K citations

  5. Cancer Genetics (United States)

    Rutherford, United States

    35 h-index

    155 publications

    13.8K citations

  6. The University of Texas MD Anderson Cancer Center

    Houston, United States

    35 h-index

    173 publications

    18.5K citations

  7. Memorial Sloan Kettering Cancer Center

    New York, United States

    33 h-index

    756 publications

    75.6K citations

  8. University of Cambridge

    Cambridge, United Kingdom

    33 h-index

    192 publications

    12.7K citations

1–8 of 3.1K

Venues

  1. PubMed

    Repository · 121 publications · 5.9K citations

    38

    h-index

  2. Journal of Clinical Oncology

    39 publications · 4.9K citations

    31

    h-index

  3. Cancer

    37 publications · 1.9K citations

    25

    h-index

  4. International Journal of Cancer

    30 publications · 1.6K citations

    24

    h-index

  5. Journal of Medical Genetics

    JMG · 36 publications · 2.2K citations

    23

    h-index

1–5