Concepedia

Arginine-engrafted biodegradable polymer for the systemic delivery of therapeutic siRNA

Jagadish Beloor, Chang Seon Choi, Hye Yeong Nam, Minsun Park, Sung Hwa Kim, Andrew Jackson, Kuen Yong Lee, Sung Wan Kim, Priti Kumar, Sang‐Kyung Lee

Biomaterials · 2011 · 64 citations · 41 references

DOI

Concepts

References

41

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi et al. · Nature · 2010 · 2.5K citations · Full text

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Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

Christopher G. Willett, Yves Boucher, Emmanuelle di Tomaso et al. · Nature Medicine · 2004 · 2K citations · Full text

, , +17

Transvascular delivery of small interfering RNA to the central nervous system

Priti Kumar, Haoquan Wu, Jodi L. McBride et al. · Nature · 2007 · 1.2K citations

, , +17

Lipid-like materials for low-dose, in vivo gene silencing

Kevin T. Love, Kerry P. Mahon, Christopher G. Levins et al. · Proceedings of the National Academy of Sciences · 2010 · 965 citations · Full text

, , +17