Concepedia

House dust mite‐specific T cells in healthy non‐atopic children

Dominique Bullens, A. De. Swerdt, Ellen Dilissen, Ahmad Kasran, Richard A. Kroczek, Pascal Cadot, P. Casaer, Jan Ceuppens

Clinical & Experimental Allergy · 2005 · 28 citations · 38 references

DOI

Abstract

Allergen-specific memory T cells from healthy non-atopic children produce IL-10 and IFN-gamma (but not Th2 cytokines) and express ICOS upon stimulation. These cells might be responsible for a normal immune balance after allergen encounter in non-atopics.

References

38

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature · 1997 · 3.6K citations

Inflammation, Mucosal Immunology, T-regulatory Cell +8

Predominant T<sub>H2</sub>-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

Douglas S. Robinson, Qutayba Hamid, Sun Ying et al. · New England Journal of Medicine · 1992 · 2.8K citations

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Andreas Hutloff, Anna‐Maria Dittrich, Katja C. Beier et al. · Nature · 1999 · 1.5K citations

Signal Transduction, Autoimmune Disease, Adaptive Immune System +10

Immune Responses in Healthy and Allergic Individuals Are Characterized by a Fine Balance between Allergen-specific T Regulatory 1 and T Helper 2 Cells

Mübeccel Akdis, Johan Verhagen, Alison Taylor et al. · The Journal of Experimental Medicine · 2004 · 1.1K citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +19

Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production

Gianfranco Del Prete, Marco Carli, Fabio Almerigogna et al. · The Journal of Immunology · 1993 · 929 citations · Full text