Concepedia

ICOS co-stimulatory receptor is essential for T-cell activation and function

Chen Dong, Amy E. Juedes, Ulla Angela Temann, Sujan Shresta, James P. Allison, Nancy H. Ruddle, Richard A. Flavell

Nature · 2001 · 942 citations · 19 references

DOI

Concepts

References

19

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Andreas Hutloff, Anna‐Maria Dittrich, Katja C. Beier et al. · Nature · 1999 · 1.5K citations

, , +12

T-cell co-stimulation through B7RP-1 and ICOS

Steven K. Yoshinaga, John Whoriskey, Sanjay D. Khare et al. · Nature · 1999 · 764 citations

, , +12

Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10.

René de Waal Malefyt, Carl G. Figdor, Richard Huijbens et al. · The Journal of Immunology · 1993 · 649 citations

, , +16

Defective T Cell Differentiation in the Absence of <i>Jnk1</i>

Chen Dong, Derek Yang, Mark Wysk et al. · Science · 1998 · 588 citations

, , +17

The CD28-Related Molecule ICOS Is Required for Effective T Cell–Dependent Immune Responses

Anthony J. Coyle, Sophie M. Lehar, Clare M. Lloyd et al. · Immunity · 2000 · 513 citations · Full text

, , +12