Concepedia

The CD28-Related Molecule ICOS Is Required for Effective T Cell–Dependent Immune Responses

Anthony J. Coyle, Sophie M. Lehar, Clare M. Lloyd, Jane Tian, Tracy Delaney, Stephen Manning, Trang Nguyen, Tim Burwell, Helga Schneider, Jose Angel Gonzalo,

Immunity · 2000 · 513 citations · 54 references

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54

Enhancement of Antitumor Immunity by CTLA-4 Blockade

Dana R. Leach, Matthew F. Krummel, James P. Allison · Science · 1996 · 3.9K citations

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

Elizabeth Tivol, Frank Borriello, Alain Schweitzer et al. · Immunity · 1995 · 2.9K citations · Full text

, , +14

Interleukin-13: Central Mediator of Allergic Asthma

Marsha Wills‐Karp, Jackie Luyimbazi, Xueying Xu et al. · Science · 1998 · 2.6K citations

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CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker et al. · Immunity · 1994 · 2.2K citations

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A Cell Culture Model for T Lymphocyte Clonal Anergy

Ronald H. Schwartz · Science · 1990 · 1.9K citations

, , +17