T-cell co-stimulation through B7RP-1 and ICOS

Steven K. Yoshinaga, John Whoriskey, Sanjay D. Khare, +23

Nature

T-cell Co-stimulationSignal TransductionAdaptive Immune SystemT-regulatory CellImmunology +5

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

Sanjay D. Khare, Ildiko Sarosi, Xing-Zhong Xia, +13

Proceedings of the National Academy of Sciences

B Cell HyperplasiaImmunologyPathologyImmunotherapyInflammation +15

Taci Is a Traf-Interacting Receptor for Tall-1, a Tumor Necrosis Factor Family Member Involved in B Cell Regulation

Xing-Zhong Xia, James Treanor, Giorgio Senaldi, +18

The Journal of Experimental Medicine

T-regulatory CellImmunologyImmune RegulationCell DeathPathology +18

Spontaneous inflammatory arthritis in HLA-B27 transgenic mice lacking beta 2-microglobulin: a model of human spondyloarthropathies.

Sanjay D. Khare, H. S. Luthra, C S David

The Journal of Experimental Medicine

HistocompatibilityHuman ClassHuman SpondyloarthropathiesImmunologyDermatology +22

Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice

Sanjay D. Khare

Proceedings of the National Academy of Sciences

Tall-1 Transgenic MiceAutoimmune DiseaseAutoantibody ProductionImmunologyPathology +5

Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS

Steven K. Yoshinaga, Ming Zhang, Jeanne Pistillo, +13

International Immunology

ImmunologyImmune RegulationMolecular BiologyImmunologic MechanismInflammation +16

HLA-B27 heavy chains contribute to spontaneous inflammatory disease in B27/human beta2-microglobulin (beta2m) double transgenic mice with disrupted mouse beta2m.

Sanjay D. Khare, J Hansen, H. S. Luthra, +1

Journal of Clinical Investigation

HistocompatibilityMhc ClassImmune RegulationImmunologyPathology +20

Oral administration of an immunodominant human collagen peptide modulates collagen-induced arthritis

Sanjay D. Khare, Christopher J. Krco, Marie Griffiths, +2

The Journal of Immunology

Spontaneous Inflammatory Disease in HLA-B27 Transgenic Mice Is Independent of MHC Class II Molecules: A Direct Role for B27 Heavy Chains and Not B27-Derived Peptides

Sanjay D. Khare, Michael J. Bull, Julie A. Hanson, +2

The Journal of Immunology

Hla ImmunogeneticsImmunologyPathologyAntigen ProcessingImmunotherapy +14

A novel modality of BAFF-specific inhibitor AMG623 peptibody reduces B-cell number and improves outcomes in murine models of autoimmune disease.

Hailing Hsu, Sanjay D. Khare, Frances Lee, +10

PubMed